Is Clopidogrel The Same As Aspirin?

How do you know if clopidogrel is working?

You may notice that you bruise or bleed more easily and it will take longer to stop bleeding while you are taking clopidogrel.

This shows that clopidogrel is working.

However, if bleeding is excessive, prolonged, or you notice blood in your urine or stool, seek urgent medical advice..

Why is aspirin and clopidogrel used together?

The combination of clopidogrel and aspirin may lower the risk for major ischemic events among patients with minor ischemic stroke or high-risk transient ischemic attack compared with aspirin alone, according to results of the POINT study.

Can you eat green vegetables while taking blood thinners?

A new study suggests that — despite doctor warnings to the contrary — you can eat leafy greens rich in vitamin K if you are taking the blood thinner warfarin.

Can I drink coffee with Plavix?

Conclusions. Acute caffeine administration after clopidogrel loading appears to be associated with enhanced platelet inhibition 2 to 4 hours after clopidogrel intake. The mechanism probably involves synergistic increase in cAMP levels.

Should clopidogrel be taken in the morning or evening?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

What are the side effects of clopidogrel 75 mg?

Common side effects of clopidogrel can include:headaches or dizziness.nausea.diarrhoea or constipation.indigestion (dyspepsia)stomach ache or abdominal pain.nosebleeds.increased bleeding (your blood taking longer to clot – for example, when you cut yourself), or easy bruising.

Can I take aspirin instead of clopidogrel?

The combination of clopidogrel and aspirin is better than aspirin or clopidogrel alone in preventing another heart attack but the risk of bleeding is higher.

Is aspirin as effective as Plavix?

In many medical centers, emergency treatment of serious chest pain (acute coronary syndrome) includes Plavix along with aspirin. In one major study, the combination was 20% better at preventing a repeat heart attack, stroke, or cardiovascular-related death than aspirin alone (9.3% vs. 11.4%).

Is it OK to take clopidogrel every other day?

Conclusions: Long term dual anti-platelet therapy with aspirin 81 mg daily and clopidogrel 75 mg every other day beyond 12 months after PCI with DES may be a safe and efficacious cost-saving strategy to prevent VLST.

Is it safe to take clopidogrel long term?

Safety Announcement [ 11-06-2015 ] A U.S. Food and Drug Administration (FDA) review has determined that long-term use of the blood-thinning drug Plavix (clopidogrel) does not increase or decrease overall risk of death in patients with, or at risk for, heart disease.

How long can you stay on Plavix?

The standard recommendation is typically at least 12 months of Plavix. But the study found that six months of treatment was enough to prevent rare but deadly complications, says researcher Marco Valgimigli, MD, of the University Hospital of Ferrara, in Italy.

What can you not take with Plavix?

17, 2009 – The FDA today warned patients not to combine Plavix with Nexium, Prilosec, and nine other drugs — including Prozac and Tagamet. The drugs may make the anti-clotting drug Plavix dangerously less effective, the FDA says. They block an enzyme in the body that turns the drug into its active form.

Which effect is produced on administration of aspirin with clopidogrel?

Aspirin and clopidogrel exert their antiplatelet effects by inhibiting thromboxane A2 production and adenosine diphosphate–induced platelet aggregation pathways, respectively. Aspirin has proven benefits in primary and secondary prevention of coronary artery disease.

Which is safer aspirin or clopidogrel?

Interpretation Long-term administration of clopidogrel to patients with atherosclerotic vascular disease is more effective than aspirin in reducing the combined risk of ischaemic stroke, myocardial infarction, or vascular death.

What can I take instead of clopidogrel?

1). Besides oral anticoagulants, such as warfarin and the more recent dabigatran[9], and niche agents, such as cilostazol and ticlopidine[10,11], the most promising alternatives to clopidogrel in those with background aspirin therapy are prasugrel and ticagrelor.

Can I take aspirin instead of blood thinners?

In general, aspirin is considered to be inferior to other blood thinners for reducing stroke risk in people with nonvalvular AFib and a CHA2DS2–VASc score of 2 or higher. When it comes to bleeding risk, aspirin is also not necessarily safer than some other blood thinners.

Does clopidogrel affect blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

What foods should I avoid when taking clopidogrel?

There’s a risk that you could get a stomach ulcer. Is there any food or drink I need to avoid? Do not drink grapefruit juice while taking clopidogrel. Grapefruit juice may increase the blood-thinning effect of your medicine.

Does clopidogrel affect the liver?

Clopidogrel is a commonly prescribed antiplatelet agent that carries a rare risk of hepatotoxicity. We describe a case of severe clopidogrel-induced hepatitis with liver biopsy assessment. Prompt recognition and withdrawal of the offending agent are imperative to prevent progression and potentially fatal liver injury.

How does aspirin and clopidogrel work?

It is also used with aspirin to treat new/worsening chest pain (new heart attack, unstable angina) and to keep blood vessels open and prevent blood clots after certain procedures (such as cardiac stent). Clopidogrel works by blocking platelets from sticking together and prevents them from forming harmful clots.

Does clopidogrel affect the kidneys?

Conclusions. In summary, among patients hospitalized with ACS and treated with clopidogrel, lower levels of kidney function were associated with a greater risk of death, hospitalization for AMI, and major bleeding.