Question: Is It Safe To Take Omeprazole With Clopidogrel?

What medications should not be taken with clopidogrel?

Clopidogrel may interact with other medicationsDiabetes drug.

In most cases, repaglinide should not be taken with clopidogrel.

Stomach acid drugs (proton pump inhibitors) …

Nonsteroidal anti-inflammatory drugs (NSAIDs) …

Blood thinners.Drugs used to treat depression.

Salicylates (aspirin) …

Opioids..

Which is the safest proton pump inhibitor?

The currently available PPIs include:omeprazole (Prilosec, Prilosec OTC, Zegerid)lansoprazole (Prevacid)pantoprazole (Protonix)rabeprazole (Aciphex)esomeprazole (Nexium)dexlansoprazole (Dexilant)

What foods should you avoid if you are on blood thinners?

If you take medicine for your heart, doctors recommend staying away from some foods because of the risk of interaction….Blood thinners: Eat fewer foods with vitamin KAsparagus.Broccoli.Brussels sprouts.Cauliflower.Green onions.Kale.Parsley.Spinach.

Can clopidogrel cause leg pain?

You may have muscle pain while you’re taking Plavix. It’s not known for sure why this occurs in people taking the drug. If you have severe muscle pain while you’re taking Plavix, call your doctor right away. They can check to see what’s causing your discomfort, and they’ll recommend whether you need medical treatment.

What can you not take with omeprazole?

Common medications that may interact with omeprazole include:aminophylline or theophylline.amphetamine.ampicillin.astemizole.bisphosphonates, such as alendronate, etidronate, or risedronate.capecitabine.cefuroxime.citalopram.More items…•

How do you cure GERD permanently?

Lifestyle and home remediesMaintain a healthy weight. … Stop smoking. … Elevate the head of your bed. … Don’t lie down after a meal. … Eat food slowly and chew thoroughly. … Avoid foods and drinks that trigger reflux. … Avoid tight-fitting clothing.

What foods neutralize stomach acid?

Foods that may help reduce your symptomsVegetables. Vegetables are naturally low in fat and sugar, and they help reduce stomach acid. … Ginger. … Oatmeal. … Noncitrus fruits. … Lean meats and seafood. … Egg whites. … Healthy fats.

Can you take omeprazole with clopidogrel?

The FDA, MHRA and EMA discourage use of omeprazole and esomeprazole in patients taking clopidogrel. There is insufficient evidence regarding which PPI is least likely to interact.

Can you take omeprazole while on blood thinners?

warfarin omeprazole Using warfarin together with omeprazole may increase the risk of bleeding in rare cases. If your doctor prescribes these medications together, you may need a dose adjustment or more frequent monitoring of your prothrombin time or International Normalized Ratio (INR) to safely use both medications.

What is the best time to take clopidogrel?

You can take clopidogrel at whatever time of day you find easiest to remember, but take your doses at the same time of day each day. Most people prefer to take it in the morning, as they find this helps them to remember to take it regularly. You can take the tablet either before or after a meal.

What foods should I avoid when taking clopidogrel?

There’s a risk that you could get a stomach ulcer. Is there any food or drink I need to avoid? Do not drink grapefruit juice while taking clopidogrel. Grapefruit juice may increase the blood-thinning effect of your medicine.

What acid reflux medicine can be taken with Plavix?

– Patients who use clopidogrel and need a medication to reduce stomach acid can use antacids and most H2 blockers such as Zantac (ranitidine), Pepcid (famotidine), Axid (nizatidine), but not Tagamet and Tagamet HB (cimetidine).

Can clopidogrel upset your stomach?

Easy bleeding/bruising, stomach upset/pain, diarrhea, and constipation may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly. Although unlikely, serious bleeding in the stomach, gut, eyes, or brain may occur.

Which PPI is safe with clopidogrel?

Accordingly, some studies showed that omeprazole attenuates the antiplatelet effect of clopidogrel[13-15] but others did not confirm these findings[19,20]. In contrast, esomeprazole, lansoprazole, pantoprazole and rabeprazole did not affect platelet function in patients treated with clopidogrel[13,15,19-22].

Does clopidogrel lower blood pressure?

Arterial hypertension is associated with platelet activation, increased sCD40L levels and endothelial dysfunction suggesting that inhibition of platelet-derived sCD40L release may improve endothelial function and lower blood pressure (BP).

When should you not take clopidogrel?

If you have certain health conditions such as a peptic ulcer or bleeding disorder you should not take clopidogrel, unless advised by a specialist. You should use clopidogrel with caution if you have liver or kidney problems. Clopidogrel must not be given to anyone under 16 years old, unless under specialist advice.

Do you need PPI cover with clopidogrel?

In light of the most recent evidence, the previous advice (to avoid all PPIs unless absolutely necessary for patients taking clopidogrel) is no longer considered necessary. Nevertheless, as a precaution, concomitant use of clopidogrel with omeprazole or esomeprazole should be discouraged.

How long does it take for stomach acid to return to normal?

For most people acid levels return to normal within one to two weeks. What should I do if I develop problems?