Question: What Does The Juxtaglomerular Apparatus Produce?

What is the major function of the Juxtaglomerular apparatus?

The juxtaglomerular apparatus functions to maintain blood pressure and to act as a quality control mechanism to ensure proper glomerular flow rate and efficient sodium reabsorption.

The urethra extends from the bladder to the surface of the body.

It consists of an epithelium-lined lumen and a smooth muscle layer..

What do mesangial cells secrete?

Mesangial cells are also specialized cells and have many important functions. They secrete an extracellular matrix substance (mesangial matrix) rich in laminin and fibronectin that helps support the capillary tuft.

What is the significance of JGA in kidney function?

The juxtaglomerular apparatus is part of the kidney nephron, next to the glomerulus. It is found between afferent arteriole and the distal convoluted tubule of the same nephron. This location is critical to its function in regulating renal blood flow and glomerular filtration rate.

What enzyme is released by the Juxtaglomerular complex to regulate GFR?

ReninRenin is an enzyme that is produced by the granular cells of the afferent arteriole at the juxtaglomerular apparatus.

What is the renal corpuscle made of?

The nephron is composed of renal corpuscle and renal tubule and is the functional unit of the kidney. The renal corpuscle consists of Bowman’s capsule and glomerular capillaries, responsible for plasma filtration (image A) & (image B). Network of capillaries that invaginate into Bowman’s capsule.

Why is renin secreted?

Renin’s primary function is therefore to eventually cause an increase in blood pressure, leading to restoration of perfusion pressure in the kidneys. Renin is secreted from juxtaglomerular kidney cells, which sense changes in renal perfusion pressure, via stretch receptors in the vascular walls.

What does the Juxtaglomerular apparatus secrete?

The juxtaglomerular cells, derived from smooth muscle cells, of the afferent arteriole secrete renin when blood pressure in the arteriole falls. Renin increases blood pressure via the renin-angiotensin-aldosterone system.

What is produced by Juxtaglomerular cells?

The juxtaglomerular cells (JG cells, or granular cells) are cells in the kidney that synthesize, store, and secrete the enzyme renin. They are specialized smooth muscle cells mainly in the walls of the afferent arterioles (and some in the efferent arterioles) that deliver blood to the glomerulus.

What are the three components of the Juxtaglomerular apparatus?

The three cellular components of the apparatus are the macula densa, extraglomerular mesangial cells, and juxtaglomerular cells (also known as granular cells)[WP].

Is renin a hormone?

Renin is a central hormone in the control of blood pressure and various other physiological functions.

What is the significance of juxtaglomerular apparatus in kidney function Class 11?

Complete answer: Juxtaglomerular apparatus is an apparatus consisting of a couple of cells of the glomerulus, distal tubule, and afferent and efferent arterioles it’s involved in maintaining the glomerular filtration rate within the kidney.

What cells line the Juxtaglomerular apparatus?

Kidney: Juxtaglomerular ApparatusJuxtaglomerular cells (JG cells or granular cells) Specialized smooth muscle cells with granular cytoplasm (renin production) and prominent nucleus. … Macula densa. Consists of modified DCT cells, which are taller and have larger more prominent nuclei than adjacent cells.Lacis cells (cells of Goormaghtigh)